COVID-19 and the endothelium

There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a genera...

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Autores principales: Jung, F., Krüger-Genge, A., Franke, R.P., Hufert, F., Küpper, J.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Short Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458498/
https://www.ncbi.nlm.nih.gov/pubmed/32568187
http://dx.doi.org/10.3233/CH-209007
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author Jung, F.
Krüger-Genge, A.
Franke, R.P.
Hufert, F.
Küpper, J.-H.
author_facet Jung, F.
Krüger-Genge, A.
Franke, R.P.
Hufert, F.
Küpper, J.-H.
author_sort Jung, F.
collection PubMed
description There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions.
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spelling pubmed-74584982020-09-11 COVID-19 and the endothelium Jung, F. Krüger-Genge, A. Franke, R.P. Hufert, F. Küpper, J.-H. Clin Hemorheol Microcirc Short Paper There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions. IOS Press 2020-07-22 /pmc/articles/PMC7458498/ /pubmed/32568187 http://dx.doi.org/10.3233/CH-209007 Text en © 2020 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Paper
Jung, F.
Krüger-Genge, A.
Franke, R.P.
Hufert, F.
Küpper, J.-H.
COVID-19 and the endothelium
title COVID-19 and the endothelium
title_full COVID-19 and the endothelium
title_fullStr COVID-19 and the endothelium
title_full_unstemmed COVID-19 and the endothelium
title_short COVID-19 and the endothelium
title_sort covid-19 and the endothelium
topic Short Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458498/
https://www.ncbi.nlm.nih.gov/pubmed/32568187
http://dx.doi.org/10.3233/CH-209007
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