Gliosis Precedes Amyloid-β Deposition and Pathological Tau Accumulation in the Neuronal Cell Cycle Re-Entry Mouse Model of Alzheimer’s Disease

BACKGROUND: The presence of cell cycle markers in postmortem Alzheimer’s disease (AD) brains suggest a potential role of cell cycle activation in AD. It was shown that cell cycle activation in postmitotic neurons in mice produces Aβ and tau pathologies from endogenous mouse proteins in the absence o...

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Detalles Bibliográficos
Autores principales: Park, Kevin H.J., Barrett, Tomás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458550/
https://www.ncbi.nlm.nih.gov/pubmed/32904753
http://dx.doi.org/10.3233/ADR-200170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458550/
https://www.ncbi.nlm.nih.gov/pubmed/32904753
http://dx.doi.org/10.3233/ADR-200170

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