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Attempt to Predict A/T/N-Based Alzheimer’s Disease Cerebrospinal Fluid Biomarkers Using a Peripheral Blood DNA Methylation Clock

BACKGROUND: Although aging is the strongest risk factor for the development of Alzheimer’s disease (AD), it remains uncertain if the blood DNA methylation clock, which reflects the effect of biological aging on DNA methylation (DNAme) status of blood cells, may be used as a surrogate biomarker for A...

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Detalles Bibliográficos
Autores principales: Sato, Kenichiro, Mano, Tatsuo, Suzuki, Kazushi, Toda, Tatsushi, Iwatsubo, Takeshi, Iwata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458568/
https://www.ncbi.nlm.nih.gov/pubmed/32904719
http://dx.doi.org/10.3233/ADR-200205