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Attempt to Predict A/T/N-Based Alzheimer’s Disease Cerebrospinal Fluid Biomarkers Using a Peripheral Blood DNA Methylation Clock
BACKGROUND: Although aging is the strongest risk factor for the development of Alzheimer’s disease (AD), it remains uncertain if the blood DNA methylation clock, which reflects the effect of biological aging on DNA methylation (DNAme) status of blood cells, may be used as a surrogate biomarker for A...
Autores principales: | Sato, Kenichiro, Mano, Tatsuo, Suzuki, Kazushi, Toda, Tatsushi, Iwatsubo, Takeshi, Iwata, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458568/ https://www.ncbi.nlm.nih.gov/pubmed/32904719 http://dx.doi.org/10.3233/ADR-200205 |
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