Cargando…
Anti-EGF antibodies as surrogate biomarkers of clinical efficacy in stage IIIB/IV non-small-cell lung cancer patients treated with an optimized CIMAvax-EGF vaccination schedule
We previously reported that CIMAvax-EGF vaccine is safe, immunogenic and efficacious to treat advanced non-small-cell lung cancer (NSCLC) patients. A phase III trial was designed using an optimized immunization schedule. It included higher antigen dose and injections at multiple sites. Immune respon...
Autores principales: | Popa, Xitlally, García, Beatriz, Fuentes, Karla P., Huerta, Vivian, Alvarez, Karen, Viada, Carmen E., Neninger, Elia, Rodríguez, Pedro C., González, Zuyen, González, Amnely, Crombet, Tania, Mazorra, Zaima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458606/ https://www.ncbi.nlm.nih.gov/pubmed/32923124 http://dx.doi.org/10.1080/2162402X.2020.1762465 |
Ejemplares similares
-
Effect of blockade of the EGF system on wound healing in patients vaccinated with CIMAvax® EGF
por: Fernández Lorente, Aymara, et al.
Publicado: (2013) -
Safety, immunogenicity and preliminary efficacy of multiple-site vaccination with an Epidermal Growth Factor (EGF) based cancer vaccine in advanced non small cell lung cancer (NSCLC) patients
por: Rodriguez, Pedro C, et al.
Publicado: (2011) -
Augmenting antibody response to EGF-depleting immunotherapy: Findings from a phase I trial of CIMAvax-EGF in combination with nivolumab in advanced stage NSCLC
por: Evans, Rachel, et al.
Publicado: (2022) -
CIMAvax-EGF: A New Therapeutic Vaccine for Advanced Non-Small Cell Lung Cancer Patients
por: Saavedra, Danay, et al.
Publicado: (2017) -
Survival of NSCLC Patients Treated with Cimavax-EGF as Switch Maintenance in the Real-World Scenario
por: Flores Vega, Yoanna I., et al.
Publicado: (2023)