Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model

Clinical observations suggest that responses to cancer immunotherapy are correlated with intra-tumoral T cell receptor (TCR) clonality, tumor mutation burden (TMB) and host HLA genotype, highlighting the importance of host T cell recognition of tumor antigens. However, the dynamic interplay between...

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Detalles Bibliográficos
Autores principales: Ye, Xuan, Waite, Janelle C., Dhanik, Ankur, Gupta, Namita, Zhong, Maggie, Adler, Christina, Malahias, Evangelia, Ni, Min, Wei, Yi, Gurer, Cagan, Zhang, Wen, Macdonald, Lynn E., Murphy, Andrew J., Sleeman, Matthew A., Skokos, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458611/
https://www.ncbi.nlm.nih.gov/pubmed/32923116
http://dx.doi.org/10.1080/2162402X.2020.1758602

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