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Dexamethasone premedication suppresses vaccine-induced immune responses against cancer
Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeu...
Autores principales: | Vormehr, Mathias, Lehar, Sophie, Kranz, Lena M., Tahtinen, Siri, Oei, Yoko, Javinal, Vincent, Delamarre, Lélia, Walzer, Kerstin C., Diken, Mustafa, Kreiter, Sebastian, Mellman, Ira, Sahin, Ugur, Schartner, Jill M., Türeci, Özlem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458619/ https://www.ncbi.nlm.nih.gov/pubmed/32923115 http://dx.doi.org/10.1080/2162402X.2020.1758004 |
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