FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function

53BP1 plays a central role in dictating DNA repair choice between non-homologous end joining (NHEJ) and homologous recombination (HR), which is important for the sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis) of BRCA1-deficient cancers. In this study, we show that FOXK1 associates wi...

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Detalles Bibliográficos
Autores principales: Tang, Mengfan, Feng, Xu, Pei, Guangsheng, Srivastava, Mrinal, Wang, Chao, Chen, Zhen, Li, Siting, Zhang, Huimin, Zhao, Zhongming, Li, Xu, Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458625/
https://www.ncbi.nlm.nih.gov/pubmed/32783940
http://dx.doi.org/10.1016/j.celrep.2020.108018

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