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Turning tolerogenic into immunogenic ileal cell death through ileal microbiota: the key to unlock the mystery of colon cancer immunoscore?
Why PD-1 blockade is ineffective in the vast majority of colorectal cancers (CCs) lacking microsatellite instability but harboring high densities of tumor infiltrating T cells and follicular T helper (TFH) and B cells remained so far an open conundrum. In a recent report published in Nature Medicine...
Autores principales: | Roberti, Maria Paula, Picard, Marion, Yonekura, Satoru, Zitvogel, Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458629/ https://www.ncbi.nlm.nih.gov/pubmed/32923141 http://dx.doi.org/10.1080/2162402X.2020.1778834 |
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