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Age-related mutational signature negatively associated with immune activity and survival outcome in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is characterized by broad genomic and transcriptional heterogeneity and results in a worse prognosis than other breast cancer types. Here, we integrated genomic and transcriptomic data combined with clinicopathologic information from 538 patients with TNBC and id...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458648/ https://www.ncbi.nlm.nih.gov/pubmed/32923150 http://dx.doi.org/10.1080/2162402X.2020.1788252 |