Age-related mutational signature negatively associated with immune activity and survival outcome in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is characterized by broad genomic and transcriptional heterogeneity and results in a worse prognosis than other breast cancer types. Here, we integrated genomic and transcriptomic data combined with clinicopathologic information from 538 patients with TNBC and id...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Chong, Wei, Yang, Xiaorong, Zhang, Yuan, Sang, Shaowei, Li, Xiangchun, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458648/
https://www.ncbi.nlm.nih.gov/pubmed/32923150
http://dx.doi.org/10.1080/2162402X.2020.1788252

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