Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain

Emerging evidence suggests that histone variants are novel epigenetic regulators of memory, whereby histone H2A.Z suppresses fear memory. However, it is not clear if altered fear memory can also modify risk for PTSD, and whether these effects differ in males and females. Using conditional-inducible...

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Detalles Bibliográficos
Autores principales: Ramzan, Firyal, Creighton, Samantha D., Hall, Meaghan, Baumbach, Jennet, Wahdan, Malak, Poulson, Sandra J., Michailidis, Vassilia, Stefanelli, Gilda, Narkaj, Klotilda, Tao, Cindy S., Khan, Dure, Steininger, Carl F. D., Walters, Brandon J., Monks, D. Ashley, Martin, Loren J., Zovkic, Iva B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458907/
https://www.ncbi.nlm.nih.gov/pubmed/32868857
http://dx.doi.org/10.1038/s41598-020-71229-x

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