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Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells
The permanent transfer of specific mtDNA sequences into mammalian cells could generate improved models of mtDNA disease and support future cell-based therapies. Previous studies documented multiple biochemical changes in recipient cells shortly after mtDNA transfer, but the long-term retention and f...
Autores principales: | Dawson, Emma R., Patananan, Alexander N., Sercel, Alexander J., Teitell, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459123/ https://www.ncbi.nlm.nih.gov/pubmed/32868785 http://dx.doi.org/10.1038/s41598-020-71199-0 |
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