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Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells

The permanent transfer of specific mtDNA sequences into mammalian cells could generate improved models of mtDNA disease and support future cell-based therapies. Previous studies documented multiple biochemical changes in recipient cells shortly after mtDNA transfer, but the long-term retention and f...

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Detalles Bibliográficos
Autores principales: Dawson, Emma R., Patananan, Alexander N., Sercel, Alexander J., Teitell, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459123/
https://www.ncbi.nlm.nih.gov/pubmed/32868785
http://dx.doi.org/10.1038/s41598-020-71199-0

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