Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020

We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21–0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0–13...

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Autores principales: Poletti, Piero, Tirani, Marcello, Cereda, Danilo, Trentini, Filippo, Guzzetta, Giorgio, Marziano, Valentina, Buoro, Sabrina, Riboli, Simona, Crottogini, Lucia, Piccarreta, Raffaella, Piatti, Alessandra, Grasselli, Giacomo, Melegaro, Alessia, Gramegna, Maria, Ajelli, Marco, Merler, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459272/
https://www.ncbi.nlm.nih.gov/pubmed/32762797
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.31.2001383
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author Poletti, Piero
Tirani, Marcello
Cereda, Danilo
Trentini, Filippo
Guzzetta, Giorgio
Marziano, Valentina
Buoro, Sabrina
Riboli, Simona
Crottogini, Lucia
Piccarreta, Raffaella
Piatti, Alessandra
Grasselli, Giacomo
Melegaro, Alessia
Gramegna, Maria
Ajelli, Marco
Merler, Stefano
author_facet Poletti, Piero
Tirani, Marcello
Cereda, Danilo
Trentini, Filippo
Guzzetta, Giorgio
Marziano, Valentina
Buoro, Sabrina
Riboli, Simona
Crottogini, Lucia
Piccarreta, Raffaella
Piatti, Alessandra
Grasselli, Giacomo
Melegaro, Alessia
Gramegna, Maria
Ajelli, Marco
Merler, Stefano
author_sort Poletti, Piero
collection PubMed
description We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21–0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0–13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31–80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03–3.16).
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spelling pubmed-74592722020-09-03 Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020 Poletti, Piero Tirani, Marcello Cereda, Danilo Trentini, Filippo Guzzetta, Giorgio Marziano, Valentina Buoro, Sabrina Riboli, Simona Crottogini, Lucia Piccarreta, Raffaella Piatti, Alessandra Grasselli, Giacomo Melegaro, Alessia Gramegna, Maria Ajelli, Marco Merler, Stefano Euro Surveill Rapid Communication We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21–0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0–13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31–80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03–3.16). European Centre for Disease Prevention and Control (ECDC) 2020-08-06 /pmc/articles/PMC7459272/ /pubmed/32762797 http://dx.doi.org/10.2807/1560-7917.ES.2020.25.31.2001383 Text en This article is copyright of the authors or their affiliated institutions, 2020. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Poletti, Piero
Tirani, Marcello
Cereda, Danilo
Trentini, Filippo
Guzzetta, Giorgio
Marziano, Valentina
Buoro, Sabrina
Riboli, Simona
Crottogini, Lucia
Piccarreta, Raffaella
Piatti, Alessandra
Grasselli, Giacomo
Melegaro, Alessia
Gramegna, Maria
Ajelli, Marco
Merler, Stefano
Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title_full Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title_fullStr Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title_full_unstemmed Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title_short Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
title_sort age-specific sars-cov-2 infection fatality ratio and associated risk factors, italy, february to april 2020
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459272/
https://www.ncbi.nlm.nih.gov/pubmed/32762797
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.31.2001383
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