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Alpha-lipoic acid alters the antitumor effect of bortezomib in melanoma cells in vitro
Bortezomib (BOZ) is a proteasome inhibitor chemotherapeutic agent utilized to treat multiple myeloma and recently offered to cure melanoma. Bortezomib-induced neuropathy is one of the dose-limiting side-effects, which can be treated with antioxidants (e.g. alpha-lipoic acid—ALA and Vitamin B1—vit B1...
Autores principales: | Takács, Angéla, Lajkó, Eszter, Láng, Orsolya, Istenes, Ildikó, Kőhidai, László |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459291/ https://www.ncbi.nlm.nih.gov/pubmed/32868799 http://dx.doi.org/10.1038/s41598-020-71138-z |
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