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Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure

Pathophysiological roles of cardiac dopamine system remain unknown. Here, we show the role of dopamine D1 receptor (D1R)-expressing cardiomyocytes (CMs) in triggering heart failure-associated ventricular arrhythmia. Comprehensive single-cell resolution analysis identifies the presence of D1R-express...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Toshihiro, Sumida, Tomokazu S., Nomura, Seitaro, Satoh, Masahiro, Higo, Tomoaki, Ito, Masamichi, Ko, Toshiyuki, Fujita, Kanna, Sweet, Mary E., Sanbe, Atsushi, Yoshimi, Kenji, Manabe, Ichiro, Sasaoka, Toshikuni, Taylor, Matthew R. G., Toko, Haruhiro, Takimoto, Eiki, Naito, Atsuhiko T., Komuro, Issei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459304/ https://www.ncbi.nlm.nih.gov/pubmed/32868781 http://dx.doi.org/10.1038/s41467-020-18128-x

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