ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: implication for the two-hit hypothesis

ARID1A loss-of-function mutation accompanied by a loss of ARID1A protein expression is considered one of the most important driver events in endometriosis-associated ovarian cancer. Although our recent genomic study clarified that ARID1A loss-of-function mutations were detected in 13% of ovarian end...

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Detalles Bibliográficos
Autores principales: Yachida, Nozomi, Yoshihara, Kosuke, Suda, Kazuaki, Nakaoka, Hirofumi, Ueda, Haruka, Sugino, Kentaro, Yamaguchi, Manako, Mori, Yutaro, Yamawaki, Kaoru, Tamura, Ryo, Ishiguro, Tatsuya, Isobe, Masanori, Motoyama, Teiichi, Inoue, Ituro, Enomoto, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459315/
https://www.ncbi.nlm.nih.gov/pubmed/32868822
http://dx.doi.org/10.1038/s41598-020-71273-7

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