ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration

Animals have evolved multiple mechanisms to protect themselves from the cumulative effects of age‐related cellular damage. Here, we reveal an unexpected link between the TNF (tumour necrosis factor) inflammatory pathway, triggered by the metalloprotease ADAM17/TACE, and a lipid droplet (LD)‐mediated...

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Detalles Bibliográficos
Autores principales: Muliyil, Sonia, Levet, Clémence, Düsterhöft, Stefan, Dulloo, Iqbal, Cowley, Sally A, Freeman, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459420/
https://www.ncbi.nlm.nih.gov/pubmed/32715522
http://dx.doi.org/10.15252/embj.2020104415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459420/
https://www.ncbi.nlm.nih.gov/pubmed/32715522
http://dx.doi.org/10.15252/embj.2020104415

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