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ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration
Animals have evolved multiple mechanisms to protect themselves from the cumulative effects of age‐related cellular damage. Here, we reveal an unexpected link between the TNF (tumour necrosis factor) inflammatory pathway, triggered by the metalloprotease ADAM17/TACE, and a lipid droplet (LD)‐mediated...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459420/ https://www.ncbi.nlm.nih.gov/pubmed/32715522 http://dx.doi.org/10.15252/embj.2020104415 |