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Sp3 Transcription Factor Cooperates with the Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein To Synergistically Activate Specific Viral and Cellular Gene Promoters

The Kaposi’s sarcoma-associated herpesvirus (KSHV)-encoded open reading frame 50 (ORF50) protein is the key transactivator responsible for the latent-to-lytic switch. Here, we investigated the transcriptional activation of the ORF56 gene (encoding a primase protein) by ORF50 and successfully identif...

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Detalles Bibliográficos
Autores principales:	Chen, Li-Yu, Chen, Lee-Wen, Peng, Kuo-Ti, Hung, Chien-Hui, Chang, Pey-Jium, Wang, Shie-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459565/ https://www.ncbi.nlm.nih.gov/pubmed/32641483 http://dx.doi.org/10.1128/JVI.01143-20

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