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Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction

Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidenc...

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Detalles Bibliográficos
Autores principales: Koirala, Pratistha, Moon, Ashley S, Chuang, Linus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459574/
https://www.ncbi.nlm.nih.gov/pubmed/32784719
http://dx.doi.org/10.3390/diagnostics10080568
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author Koirala, Pratistha
Moon, Ashley S
Chuang, Linus
author_facet Koirala, Pratistha
Moon, Ashley S
Chuang, Linus
author_sort Koirala, Pratistha
collection PubMed
description Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients.
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spelling pubmed-74595742020-09-02 Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction Koirala, Pratistha Moon, Ashley S Chuang, Linus Diagnostics (Basel) Review Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients. MDPI 2020-08-07 /pmc/articles/PMC7459574/ /pubmed/32784719 http://dx.doi.org/10.3390/diagnostics10080568 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Koirala, Pratistha
Moon, Ashley S
Chuang, Linus
Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title_full Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title_fullStr Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title_full_unstemmed Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title_short Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
title_sort clinical utility of preoperative assessment in ovarian cancer cytoreduction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459574/
https://www.ncbi.nlm.nih.gov/pubmed/32784719
http://dx.doi.org/10.3390/diagnostics10080568
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