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Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction
Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidenc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459574/ https://www.ncbi.nlm.nih.gov/pubmed/32784719 http://dx.doi.org/10.3390/diagnostics10080568 |
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author | Koirala, Pratistha Moon, Ashley S Chuang, Linus |
author_facet | Koirala, Pratistha Moon, Ashley S Chuang, Linus |
author_sort | Koirala, Pratistha |
collection | PubMed |
description | Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients. |
format | Online Article Text |
id | pubmed-7459574 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74595742020-09-02 Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction Koirala, Pratistha Moon, Ashley S Chuang, Linus Diagnostics (Basel) Review Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients. MDPI 2020-08-07 /pmc/articles/PMC7459574/ /pubmed/32784719 http://dx.doi.org/10.3390/diagnostics10080568 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Koirala, Pratistha Moon, Ashley S Chuang, Linus Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title | Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title_full | Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title_fullStr | Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title_full_unstemmed | Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title_short | Clinical Utility of Preoperative Assessment in Ovarian Cancer Cytoreduction |
title_sort | clinical utility of preoperative assessment in ovarian cancer cytoreduction |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459574/ https://www.ncbi.nlm.nih.gov/pubmed/32784719 http://dx.doi.org/10.3390/diagnostics10080568 |
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