Cargando…

Antimicrobial Peptide TP4 Targets Mitochondrial Adenine Nucleotide Translocator 2

Tilapia piscidin (TP) 4 is an antimicrobial peptide derived from Nile tilapia (Oreochromis niloticus), which shows broad-spectrum antibacterial activity and excellent cancer-killing ability in vitro and in vivo. Like many other antimicrobial peptides, TP4 treatment causes mitochondrial toxicity in c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Bor-Chyuan, Liu, Yi-Chung, Ting, Chen-Hung, Lyu, Ping-Chiang, Chen, Jyh-Yih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459631/ https://www.ncbi.nlm.nih.gov/pubmed/32784874 http://dx.doi.org/10.3390/md18080417

Ejemplares similares

Nile Tilapia Derived Antimicrobial Peptide TP4 Exerts Antineoplastic Activity Through Microtubule Disruption
por: Ting, Chen-Hung, et al.
Publicado: (2018)

Antimicrobial Peptide TP4 Induces ROS-Mediated Necrosis by Triggering Mitochondrial Dysfunction in Wild-Type and Mutant p53 Glioblastoma Cells
por: Su, Bor-Chyuan, et al.
Publicado: (2019)

Marine Antimicrobial Peptide TP4 Exerts Anticancer Effects on Human Synovial Sarcoma Cells via Calcium Overload, Reactive Oxygen Species Production and Mitochondrial Hyperpolarization
por: Su, Bor-Chyuan, et al.
Publicado: (2021)

Study of the Antimicrobial Activity of Tilapia Piscidin 3 (TP3) and TP4 and Their Effects on Immune Functions in Hybrid Tilapia (Oreochromis spp.)
por: Pan, Chieh-Yu, et al.
Publicado: (2017)

Antimicrobial Peptide Epinecidin-1 Modulates MyD88 Protein Levels via the Proteasome Degradation Pathway
por: Su, Bor-Chyuan, et al.
Publicado: (2017)

Depletion of Toxoplasma adenine nucleotide translocator leads to defects in mitochondrial morphology
por: Wu, Yihan, et al.
Publicado: (2022)

Targeting FOSB with a cationic antimicrobial peptide, TP4, for treatment of triple-negative breast cancer
por: Ting, Chen-Hung, et al.
Publicado: (2016)

The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions
por: Jiang, Hui, et al.
Publicado: (2016)

Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis
por: Liu, Chia-Wen, et al.
Publicado: (2021)

Adenine Nucleotide Translocator Transports Haem Precursors into Mitochondria
por: Azuma, Motoki, et al.
Publicado: (2008)

Adenine Nucleotide Translocator as a Regulator of Mitochondrial Function: Implication in the Pathogenesis of Metabolic Syndrome
por: Kim, Eun Hee, et al.
Publicado: (2010)

The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023)

Adenine Nucleotide Translocase, Mitochondrial Stress, and Degenerative Cell Death
por: Liu, Yaxin, et al.
Publicado: (2013)

The Role of Adenine Nucleotide Translocase in the Mitochondrial Permeability Transition
por: Brustovetsky, Nickolay
Publicado: (2020)

Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2
por: Jacotot, Etienne, et al.
Publicado: (2001)

Nile Tilapia Derived TP4 Shows Broad Cytotoxicity toward to Non-Small-Cell Lung Cancer Cells
por: Ting, Chen-Hung, et al.
Publicado: (2018)

Calcium-Dependent Calpain Activation-Mediated Mitochondrial Dysfunction and Oxidative Stress Are Required for Cytotoxicity of Epinecidin-1 in Human Synovial Sarcoma SW982 Cells
por: Su, Bor-Chyuan, et al.
Publicado: (2020)

The product of the Herpes simplex virus 1 UL7 gene interacts with a mitochondrial protein, adenine nucleotide translocator 2
por: Tanaka, Michiko, et al.
Publicado: (2008)

Hypothesis on Skeletal Muscle Aging: Mitochondrial Adenine Nucleotide Translocator Decreases Reactive Oxygen Species Production While Preserving Coupling Efficiency
por: Diolez, Philippe, et al.
Publicado: (2015)

Elamipretide Improves ADP Sensitivity in Aged Mitochondria by Increasing Uptake through the Adenine Nucleotide Translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023)

Investigations on the Wound Healing Potential of Tilapia Piscidin (TP)2-5 and TP2-6
por: Liu, Chia-Wen, et al.
Publicado: (2022)

Efficacy of the antimicrobial peptide TP4 against Helicobacter pylori infection: in vitro membrane perturbation via micellization and in vivo suppression of host immune responses in a mouse model
por: Narayana, Jayaram Lakshmaiah, et al.
Publicado: (2015)

ADENINE NUCLEOTIDE-INDUCED CONTRACTION OF THE INNER MITOCHONDRIAL MEMBRANE : I. General Characterization
por: Stoner, Clinton D., et al.
Publicado: (1973)

Interaction of Agaric Acid with the Adenine Nucleotide Translocase Induces Mitochondrial Oxidative Stress
por: Chávez, Edmundo, et al.
Publicado: (2020)

Insights into the equilibrium structure and translocation mechanism of TP1, a spontaneous membrane-translocating peptide
por: Muñoz-Gacitúa, Diego, et al.
Publicado: (2022)

A Walk in the Memory, from the First Functional Approach up to Its Regulatory Role of Mitochondrial Bioenergetic Flow in Health and Disease: Focus on the Adenine Nucleotide Translocator
por: Atlante, Anna, et al.
Publicado: (2021)

Epinecidin-1 Protects against Methicillin Resistant Staphylococcus aureus Infection and Sepsis in Pyemia Pigs
por: Huang, Han-Ning, et al.
Publicado: (2019)

ADENINE NUCLEOTIDE-INDUCED CONTRACTION OF THE INNER MITOCHONDRIAL MEMBRANE : II. Effect of Bongkrekic Acid
por: Stoner, Clinton D., et al.
Publicado: (1973)

Molecular Dynamics Simulations of Creatine Kinase and Adenine Nucleotide Translocase in Mitochondrial Membrane Patch
por: Karo, Jaanus, et al.
Publicado: (2012)

Expression of Adenine Nucleotide Translocator Correlates with the IL-4-induced lymphocyte survival: Role of PI3K and MAPK
por: Jang, Ji-Young, et al.
Publicado: (2001)

THE LOCATION OF ADENINE NUCLEOTIDE IN THE STRIATED MUSCLE OF THE TOAD
por: Hill, D. K.
Publicado: (1964)

A Pilot Safety Assessment for Recombinant Epinephelus lanceolatus Piscidin Yeast Powder as a Drug Food Additive after Subacute and Subchronic Administration to SD Rats
por: Su, Bor-Chyuan, et al.
Publicado: (2020)

Human adenine nucleotide translocases physically and functionally interact with respirasomes
por: Lu, Ya-Wen, et al.
Publicado: (2017)

TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors
por: Law, Alick KT, et al.
Publicado: (2004)

Interventions in Nicotinamide Adenine Dinucleotide Metabolism, the Intestinal Microbiota and Microcin Peptide Antimicrobials
por: Baquero, Fernando, et al.
Publicado: (2022)

Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4
por: Chang, Ting-Wei, et al.
Publicado: (2017)

Structural basis of AMPK regulation by adenine nucleotides and glycogen
por: Li, Xiaodan, et al.
Publicado: (2015)

Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy
por: Miller, Spencer G., et al.
Publicado: (2019)

High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation
por: Azzu, Vian, et al.
Publicado: (2008)

The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase
por: Park, Danielle, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_00mpqambua4brlaaj9vevaf68h