13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity against Oral Cancer Cells through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts

13-Acetoxysarcocrassolide (13-AC), a marine cytotoxic product isolated from the alcyonacean coral Lobophytum crassum, exhibited potent antitumor and immunostimulant effects as reported in previous studies. However, the 13-AC antitumor mechanism of action against oral cancer cells remains unclear. Th...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Chang, Peng, Bo-Rong, Hsu, Kai-Cheng, El-Shazly, Mohamed, Shih, Shou-Ping, Lin, Tony Eight, Kuo, Fu-Wen, Chou, Yi-Cheng, Lin, Hung-Yu, Lu, Mei-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459766/
https://www.ncbi.nlm.nih.gov/pubmed/32718084
http://dx.doi.org/10.3390/md18080382

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