Cargando…
Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach
There is a significant need to combat the growing challenge of antibacterial drug resistance. We have previously developed a whole-animal dual-screening platform that first used the nematode Caenorhabditis elegans, to identify low-toxicity antibacterial hits in a high-throughput format. The hits wer...
Autores principales: | Khader, Rajamohammed, Tharmalingam, Nagendran, Mishra, Biswajit, Felix, LewisOscar, Ausubel, Frederick M., Kelso, Michael J., Mylonakis, Eleftherios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459823/ https://www.ncbi.nlm.nih.gov/pubmed/32726955 http://dx.doi.org/10.3390/antibiotics9080449 |
Ejemplares similares
-
A Substituted Diphenyl Amide Based Novel Scaffold Inhibits Staphylococcus aureus Virulence in a Galleria mellonella Infection Model
por: Mishra, Biswajit, et al.
Publicado: (2021) -
Novel Cecropin-4 Derived Peptides against Methicillin-Resistant Staphylococcus aureus
por: Peng, Jian, et al.
Publicado: (2021) -
In Vitro and In Vivo Bactericidal and Antibiofilm Efficacy of Alpha Mangostin Against Staphylococcus aureus Persister Cells
por: Felix, LewisOscar, et al.
Publicado: (2022) -
The Anti-virulence Efficacy of 4-(1,3-Dimethyl-2,3-Dihydro-1H-Benzimidazol-2-yl)Phenol Against Methicillin-Resistant Staphylococcus aureus
por: Tharmalingam, Nagendran, et al.
Publicado: (2019) -
Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses
por: Pukkila-Worley, Read, et al.
Publicado: (2011)