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The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania

Efforts to map the burden of infections globally have shown a high prevalence of genital infections, including Chlamydia trachomatis, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women in Pemba Island, Tan...

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Autores principales: Juliana, Naomi C.A., Deb, Saikat, Ouburg, Sander, Chauhan, Aishwarya, Pleijster, Jolein, Ali, Said M., Morré, Servaas A., Sazawal, Sunil, Ambrosino, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459925/
https://www.ncbi.nlm.nih.gov/pubmed/32751883
http://dx.doi.org/10.3390/pathogens9080625
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author Juliana, Naomi C.A.
Deb, Saikat
Ouburg, Sander
Chauhan, Aishwarya
Pleijster, Jolein
Ali, Said M.
Morré, Servaas A.
Sazawal, Sunil
Ambrosino, Elena
author_facet Juliana, Naomi C.A.
Deb, Saikat
Ouburg, Sander
Chauhan, Aishwarya
Pleijster, Jolein
Ali, Said M.
Morré, Servaas A.
Sazawal, Sunil
Ambrosino, Elena
author_sort Juliana, Naomi C.A.
collection PubMed
description Efforts to map the burden of infections globally have shown a high prevalence of genital infections, including Chlamydia trachomatis, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women in Pemba Island, Tanzania. Vaginal swabs were collected during pregnancy and stored in eNAT buffer. Detection of C. trachomatis, Neisseria gonorrheae, Trichomonas vaginalis, and Mycoplasma genitalium pathogens was performed by PCR using validated detection kits. Vaginal samples of 439 pregnant women between 16 and 48 years were tested. In fifty-five (12.5%) of them, at least one genital pathogen was detected. The most prevalent pathogen was T. vaginalis (7.1%), followed by C. trachomatis (4.6%) and M. genitalium (2.1%). None of the vaginal samples tested positive for N. gonorrheae. Consequently, among positive samples, 7.3% were for C. trachomatis and at least one other genital pathogen. This study provides insights on the burden of the four studied genital infections, and on the coinfections among pregnant women in Pemba Island, Tanzania. These results offer a starting point that can be useful to design further research in the field of maternal and child health in Pemba Island.
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spelling pubmed-74599252020-09-02 The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania Juliana, Naomi C.A. Deb, Saikat Ouburg, Sander Chauhan, Aishwarya Pleijster, Jolein Ali, Said M. Morré, Servaas A. Sazawal, Sunil Ambrosino, Elena Pathogens Article Efforts to map the burden of infections globally have shown a high prevalence of genital infections, including Chlamydia trachomatis, in sub-Saharan Africa. This retrospective study aimed to investigate the prevalence of selected non-viral genital infections among pregnant women in Pemba Island, Tanzania. Vaginal swabs were collected during pregnancy and stored in eNAT buffer. Detection of C. trachomatis, Neisseria gonorrheae, Trichomonas vaginalis, and Mycoplasma genitalium pathogens was performed by PCR using validated detection kits. Vaginal samples of 439 pregnant women between 16 and 48 years were tested. In fifty-five (12.5%) of them, at least one genital pathogen was detected. The most prevalent pathogen was T. vaginalis (7.1%), followed by C. trachomatis (4.6%) and M. genitalium (2.1%). None of the vaginal samples tested positive for N. gonorrheae. Consequently, among positive samples, 7.3% were for C. trachomatis and at least one other genital pathogen. This study provides insights on the burden of the four studied genital infections, and on the coinfections among pregnant women in Pemba Island, Tanzania. These results offer a starting point that can be useful to design further research in the field of maternal and child health in Pemba Island. MDPI 2020-07-31 /pmc/articles/PMC7459925/ /pubmed/32751883 http://dx.doi.org/10.3390/pathogens9080625 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Juliana, Naomi C.A.
Deb, Saikat
Ouburg, Sander
Chauhan, Aishwarya
Pleijster, Jolein
Ali, Said M.
Morré, Servaas A.
Sazawal, Sunil
Ambrosino, Elena
The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_full The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_fullStr The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_full_unstemmed The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_short The Prevalence of Chlamydia trachomatis and Three Other Non-Viral Sexually Transmitted Infections among Pregnant Women in Pemba Island Tanzania
title_sort prevalence of chlamydia trachomatis and three other non-viral sexually transmitted infections among pregnant women in pemba island tanzania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459925/
https://www.ncbi.nlm.nih.gov/pubmed/32751883
http://dx.doi.org/10.3390/pathogens9080625
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