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Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers

SIMPLE SUMMARY: The effect of oral supplementation of Tamoxifen on productive and reproductive efficiencies and carcass characteristics of two broiler breeds was investigated in the current study. Tamoxifen supplementation can improve growth performance and carcass efficiency of broilers without cha...

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Autores principales: Younis, Mona E.M., Aboelnour, Asmaa, Swelum, Ayman A., Ghoneim, Hanan A., Abd El-Hack, Mohamed E., Khafaga, Asmaa F., Al-Ghadi, Muath Q., Al-Himadi, Ahmed R., Almutairi, Bader O., Ammari, Aiman A., Ghanima, Mahmoud M. Abo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459955/
https://www.ncbi.nlm.nih.gov/pubmed/32781769
http://dx.doi.org/10.3390/ani10081367
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author Younis, Mona E.M.
Aboelnour, Asmaa
Swelum, Ayman A.
Ghoneim, Hanan A.
Abd El-Hack, Mohamed E.
Khafaga, Asmaa F.
Al-Ghadi, Muath Q.
Al-Himadi, Ahmed R.
Almutairi, Bader O.
Ammari, Aiman A.
Ghanima, Mahmoud M. Abo
author_facet Younis, Mona E.M.
Aboelnour, Asmaa
Swelum, Ayman A.
Ghoneim, Hanan A.
Abd El-Hack, Mohamed E.
Khafaga, Asmaa F.
Al-Ghadi, Muath Q.
Al-Himadi, Ahmed R.
Almutairi, Bader O.
Ammari, Aiman A.
Ghanima, Mahmoud M. Abo
author_sort Younis, Mona E.M.
collection PubMed
description SIMPLE SUMMARY: The effect of oral supplementation of Tamoxifen on productive and reproductive efficiencies and carcass characteristics of two broiler breeds was investigated in the current study. Tamoxifen supplementation can improve growth performance and carcass efficiency of broilers without changing the sex hormonal profile, however, treatment of broiler chicken with Tamoxifen in different doses caused a gradual decrease in follicle production rate and eventually led to an increase of the atretic follicles in different stages of atresia. Further research is required to estimate the best concentration required for each breed. ABSTRACT: This research was aimed at estimating the effect of oral supplementation of Tamoxifen on productive efficiency, carcass characteristics, hormonal profile and gonadal structure of two broiler breeds. One hundred and eighty chicks of each breed of Avian48 and Arbor Acres were divided into three groups: control group; TAM10 group, supplied with 10 mg Tamoxifen/kg of body weight at 3, 5, 7 and 9 days of life; and TAM20 group, supplied at the same intervals with 20 mg Tamoxifen/kg of body weight. Both levels of Tamoxifen improved productive performance at early ages, but Arbor Acres produced better results with TAM20 levels than TAM10, while Avian48 breeds reacted adversely. On the contrary, Tamoxifen supplementation significantly decreased feed intake and feed conversion (after the first two weeks of life) compared to control with a higher level of decrease reported for TAM20 treatments than TAM10 and for Arbor Acres compared to Avian48 breed. Carcass traits were not affected significantly with Tamoxifen supplementation compared to control although Arbor Acres responded better to TAM20 and Avian48 for TAM10. With regard to the effect of Tamoxifen (TAM) on sex hormones, it could be concluded that TAM10 treatments showed a stimulating effect on the level of such hormones as compared with the TAM20 group with the most favourable results being clearly detectable in 42-day-old birds although both concentrations of Tamoxifen did not differ significantly from control. However, treatment of broiler chickens with Tamoxifen in different doses caused a gradual decrease in follicle production rate and eventually led to an increase of the atretic follicles in different stages of atresia. Finally, we can conclude that Tamoxifen supplementation can improve performance and carcass efficiency of broilers without changing the hormonal profile, however much research is required to estimate the best concentration required for each breed.
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spelling pubmed-74599552020-09-02 Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers Younis, Mona E.M. Aboelnour, Asmaa Swelum, Ayman A. Ghoneim, Hanan A. Abd El-Hack, Mohamed E. Khafaga, Asmaa F. Al-Ghadi, Muath Q. Al-Himadi, Ahmed R. Almutairi, Bader O. Ammari, Aiman A. Ghanima, Mahmoud M. Abo Animals (Basel) Article SIMPLE SUMMARY: The effect of oral supplementation of Tamoxifen on productive and reproductive efficiencies and carcass characteristics of two broiler breeds was investigated in the current study. Tamoxifen supplementation can improve growth performance and carcass efficiency of broilers without changing the sex hormonal profile, however, treatment of broiler chicken with Tamoxifen in different doses caused a gradual decrease in follicle production rate and eventually led to an increase of the atretic follicles in different stages of atresia. Further research is required to estimate the best concentration required for each breed. ABSTRACT: This research was aimed at estimating the effect of oral supplementation of Tamoxifen on productive efficiency, carcass characteristics, hormonal profile and gonadal structure of two broiler breeds. One hundred and eighty chicks of each breed of Avian48 and Arbor Acres were divided into three groups: control group; TAM10 group, supplied with 10 mg Tamoxifen/kg of body weight at 3, 5, 7 and 9 days of life; and TAM20 group, supplied at the same intervals with 20 mg Tamoxifen/kg of body weight. Both levels of Tamoxifen improved productive performance at early ages, but Arbor Acres produced better results with TAM20 levels than TAM10, while Avian48 breeds reacted adversely. On the contrary, Tamoxifen supplementation significantly decreased feed intake and feed conversion (after the first two weeks of life) compared to control with a higher level of decrease reported for TAM20 treatments than TAM10 and for Arbor Acres compared to Avian48 breed. Carcass traits were not affected significantly with Tamoxifen supplementation compared to control although Arbor Acres responded better to TAM20 and Avian48 for TAM10. With regard to the effect of Tamoxifen (TAM) on sex hormones, it could be concluded that TAM10 treatments showed a stimulating effect on the level of such hormones as compared with the TAM20 group with the most favourable results being clearly detectable in 42-day-old birds although both concentrations of Tamoxifen did not differ significantly from control. However, treatment of broiler chickens with Tamoxifen in different doses caused a gradual decrease in follicle production rate and eventually led to an increase of the atretic follicles in different stages of atresia. Finally, we can conclude that Tamoxifen supplementation can improve performance and carcass efficiency of broilers without changing the hormonal profile, however much research is required to estimate the best concentration required for each breed. MDPI 2020-08-06 /pmc/articles/PMC7459955/ /pubmed/32781769 http://dx.doi.org/10.3390/ani10081367 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Younis, Mona E.M.
Aboelnour, Asmaa
Swelum, Ayman A.
Ghoneim, Hanan A.
Abd El-Hack, Mohamed E.
Khafaga, Asmaa F.
Al-Ghadi, Muath Q.
Al-Himadi, Ahmed R.
Almutairi, Bader O.
Ammari, Aiman A.
Ghanima, Mahmoud M. Abo
Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title_full Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title_fullStr Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title_full_unstemmed Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title_short Impact of Oral Supplementation of Different Levels of Tamoxifen on Productive and Reproductive Efficiencies and Carcass Traits of Avian48 and Arbor Acres Broilers
title_sort impact of oral supplementation of different levels of tamoxifen on productive and reproductive efficiencies and carcass traits of avian48 and arbor acres broilers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459955/
https://www.ncbi.nlm.nih.gov/pubmed/32781769
http://dx.doi.org/10.3390/ani10081367
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