Cargando…

Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes

Aβ, IAPP, α-synuclein, and prion proteins belong to the amyloidogenic intrinsically disordered proteins’ family; indeed, they lack well defined secondary and tertiary structures. It is generally acknowledged that they are involved, respectively, in Alzheimer’s, Type II Diabetes Mellitus, Parkinson’s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scollo, Federica, La Rosa, Carmelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459996/ https://www.ncbi.nlm.nih.gov/pubmed/32784399 http://dx.doi.org/10.3390/life10080144

Ejemplares similares

α-Helical Structures Drive Early Stages of Self-Assembly of Amyloidogenic Amyloid Polypeptide Aggregate Formation in Membranes
por: Pannuzzo, Martina, et al.
Publicado: (2013)

Misfolding of Amyloidogenic Proteins and Their Interactions with Membranes
por: Relini, Annalisa, et al.
Publicado: (2013)

Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins
por: Das, Swagata, et al.
Publicado: (2014)

Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association
por: Santos, Jaime, et al.
Publicado: (2021)

CARs-DB: A Database of Cryptic Amyloidogenic Regions in Intrinsically Disordered Proteins
por: Pintado-Grima, Carlos, et al.
Publicado: (2022)

Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules
por: Cawood, Emma E., et al.
Publicado: (2020)

Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble
por: Zhu, Shaolong, et al.
Publicado: (2015)

Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein
por: Majewski, Jaroslaw, et al.
Publicado: (2020)

Prediction of Amyloidogenic and Disordered Regions in Protein Chains
por: Galzitskaya, Oxana V, et al.
Publicado: (2006)

HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders
por: Zeinolabediny, Yasmin, et al.
Publicado: (2017)

The C-terminal amyloidogenic peptide contributes to self-assembly of Avibirnavirus viral protease
por: Zheng, Xiaojuan, et al.
Publicado: (2015)

Insights into Membrane Curvature Sensing and Membrane Remodeling by Intrinsically Disordered Proteins and Protein Regions
por: Has, Chandra, et al.
Publicado: (2022)

Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage
por: Manral, Pallavi, et al.
Publicado: (2015)

Folding and self-assembly of short intrinsically disordered peptides and protein regions
por: Argudo, Pablo G., et al.
Publicado: (2021)

Self-Assembly of Tunable Intrinsically Disordered Peptide Amphiphiles
por: Ehm, Tamara, et al.
Publicado: (2022)

Structural Insight of Amyloidogenic Intermediates of Human Insulin
por: Dolui, Sandip, et al.
Publicado: (2018)

The Diagnostic Potential of Amyloidogenic Proteins
por: Jin, Yiyun, et al.
Publicado: (2021)

Concentration and time-dependent amyloidogenic characteristics of intrinsically disordered N-terminal region of Saccharomyces cerevisiae Stm1
por: Subbaiah S P, Venkata, et al.
Publicado: (2023)

Visualization of APP and BACE-1 approximation in neurons: new insights into the amyloidogenic pathway
por: Das, Utpal, et al.
Publicado: (2015)

Intrinsically Disordered Tardigrade Proteins Self‐Assemble into Fibrous Gels in Response to Environmental Stress
por: Malki, Anas, et al.
Publicado: (2021)

An Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase
por: Matthes, Dirk, et al.
Publicado: (2016)

Predicting Amyloidogenic Proteins in the Proteomes of Plants
por: Antonets, Kirill S., et al.
Publicado: (2017)

Evolvability of Amyloidogenic Proteins in Human Brain
por: Hashimoto, Makoto, et al.
Publicado: (2018)

Intrinsic Disorder in Protein Interactions: Insights From a Comprehensive Structural Analysis
por: Fong, Jessica H., et al.
Publicado: (2009)

NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins
por: Camacho-Zarco, Aldo R., et al.
Publicado: (2022)

Theater in the Self-Cleaning Cell: Intrinsically Disordered Proteins or Protein Regions Acting with Membranes in Autophagy
por: Popelka, Hana, et al.
Publicado: (2022)

Intrinsically disordered proteins drive membrane curvature
por: Busch, David J., et al.
Publicado: (2015)

Unveiling the Metal-Dependent Aggregation Properties of the C-terminal Region of Amyloidogenic Intrinsically Disordered Protein Isoforms DPF3b and DPF3a
por: Leyder, Tanguy, et al.
Publicado: (2022)

Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes
por: Farrugia, Maria Ylenia, et al.
Publicado: (2020)

Interactions of amyloidogenic proteins with mitochondrial protein import machinery in aging-related neurodegenerative diseases
por: Reed, Ashley L., et al.
Publicado: (2023)

Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System
por: Buxbaum, Joel N., et al.
Publicado: (2017)

Controversial Properties of Amyloidogenic Proteins and Peptides: New Data in the COVID Era
por: Surguchov, Andrei, et al.
Publicado: (2023)

Amyloidogenic Regions and Interaction Surfaces Overlap in Globular Proteins Related to Conformational Diseases
por: Castillo, Virginia, et al.
Publicado: (2009)

Bioinformatic identification of previously unrecognized amyloidogenic proteins
por: Rosenberg, Gregory M., et al.
Publicado: (2022)

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro
por: Ozawa, Daisaku, et al.
Publicado: (2016)

Modulating Hierarchical Self-Assembly In Thermoresponsive Intrinsically Disordered Proteins Through High-Temperature Incubation Time
por: Sethi, Vaishali, et al.
Publicado: (2023)

Modulating Hierarchical Self-Assembly In Thermoresponsive Intrinsically Disordered Proteins Through High-Temperature Incubation Time
por: Sethi, Vaishali, et al.
Publicado: (2023)

Engagement of intrinsic disordered proteins in protein–protein interaction
por: Roterman, Irena, et al.
Publicado: (2023)

SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration
por: Idrees, Danish, et al.
Publicado: (2021)

Structural Insight into Tau Protein’s Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation
por: Luo, Yin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k5ir9tmpgro41676u2qhsjm5ge