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An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification

Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on r...

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Autores principales: Aamir, Muhammad, Irfan, Muhammad, Ali, Tariq, Ali, Ghulam, Shaf, Ahmad, S, Alqahtani Saeed, Al-Beshri, Ali, Alasbali, Tariq, Mahnashi, Mater H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460037/
https://www.ncbi.nlm.nih.gov/pubmed/32824682
http://dx.doi.org/10.3390/diagnostics10080602
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author Aamir, Muhammad
Irfan, Muhammad
Ali, Tariq
Ali, Ghulam
Shaf, Ahmad
S, Alqahtani Saeed
Al-Beshri, Ali
Alasbali, Tariq
Mahnashi, Mater H.
author_facet Aamir, Muhammad
Irfan, Muhammad
Ali, Tariq
Ali, Ghulam
Shaf, Ahmad
S, Alqahtani Saeed
Al-Beshri, Ali
Alasbali, Tariq
Mahnashi, Mater H.
author_sort Aamir, Muhammad
collection PubMed
description Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on retinal fundus images to diagnose glaucoma. We collected a retinal fundus images database from the local hospital. The fundus images are pre-processed by an adaptive histogram equalizer to reduce the noise of images. The ML-DCNN architecture is used for features extraction and classification into two phases, one for glaucoma detection known as detection-net and the second one is classification-net used for classification of affected retinal glaucoma images into three different categories: Advanced, Moderate and Early. The proposed model is tested on 1338 retinal glaucoma images and performance is measured in the form of different statistical terms known as sensitivity (SE), specificity (SP), accuracy (ACC), and precision (PRE). On average, SE of 97.04%, SP of 98.99%, ACC of 99.39%, and PRC of 98.2% are achieved. The obtained outcomes are comparable to the state-of-the-art systems and achieved competitive results to solve the glaucoma eye disease problems for complex glaucoma eye disease cases.
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spelling pubmed-74600372020-09-02 An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification Aamir, Muhammad Irfan, Muhammad Ali, Tariq Ali, Ghulam Shaf, Ahmad S, Alqahtani Saeed Al-Beshri, Ali Alasbali, Tariq Mahnashi, Mater H. Diagnostics (Basel) Article Glaucoma, an eye disease, occurs due to Retinal damages and it is an ordinary cause of blindness. Most of the available examining procedures are too long and require manual instructions to use them. In this work, we proposed a multi-level deep convolutional neural network (ML-DCNN) architecture on retinal fundus images to diagnose glaucoma. We collected a retinal fundus images database from the local hospital. The fundus images are pre-processed by an adaptive histogram equalizer to reduce the noise of images. The ML-DCNN architecture is used for features extraction and classification into two phases, one for glaucoma detection known as detection-net and the second one is classification-net used for classification of affected retinal glaucoma images into three different categories: Advanced, Moderate and Early. The proposed model is tested on 1338 retinal glaucoma images and performance is measured in the form of different statistical terms known as sensitivity (SE), specificity (SP), accuracy (ACC), and precision (PRE). On average, SE of 97.04%, SP of 98.99%, ACC of 99.39%, and PRC of 98.2% are achieved. The obtained outcomes are comparable to the state-of-the-art systems and achieved competitive results to solve the glaucoma eye disease problems for complex glaucoma eye disease cases. MDPI 2020-08-18 /pmc/articles/PMC7460037/ /pubmed/32824682 http://dx.doi.org/10.3390/diagnostics10080602 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aamir, Muhammad
Irfan, Muhammad
Ali, Tariq
Ali, Ghulam
Shaf, Ahmad
S, Alqahtani Saeed
Al-Beshri, Ali
Alasbali, Tariq
Mahnashi, Mater H.
An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_full An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_fullStr An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_full_unstemmed An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_short An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
title_sort adoptive threshold-based multi-level deep convolutional neural network for glaucoma eye disease detection and classification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460037/
https://www.ncbi.nlm.nih.gov/pubmed/32824682
http://dx.doi.org/10.3390/diagnostics10080602
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