Cargando…
miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function
Downregulated microRNA-142-3p signaling contributes to the pathogenesis of endometriosis, an invasive disease where the lining of the uterus grows at ectopic locations, by yet incompletely understood mechanisms. Using bioinformatics and in vitro assays, this study identifies cytoskeletal regulation...
Autores principales: | Börschel, Christin S., Stejskalova, Anna, Schäfer, Sebastian D., Kiesel, Ludwig, Götte, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460043/ https://www.ncbi.nlm.nih.gov/pubmed/32824678 http://dx.doi.org/10.3390/biomedicines8080291 |
Ejemplares similares
-
microRNA miR-142-3p Inhibits Breast Cancer Cell Invasiveness by Synchronous Targeting of WASL, Integrin Alpha V, and Additional Cytoskeletal Elements
por: Schwickert, Alexander, et al.
Publicado: (2015) -
Rho Gtpases: Integrating Integrin Signaling
por: Ridley, Anne
Publicado: (2000) -
Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases
por: Clark, Edwin A., et al.
Publicado: (1998) -
Rho GTPase and Shroom direct planar polarized actomyosin contractility during convergent extension
por: Simões, Sérgio de Matos, et al.
Publicado: (2014) -
Control of developmental networks by Rac/Rho small GTPases: How cytoskeletal changes during embryogenesis are orchestrated
por: Sáenz‐Narciso, Beatriz, et al.
Publicado: (2016)