Cargando…
α-Conotoxin as Potential to α7-nAChR Recombinant Expressed in Escherichia coli
α7 nicotinic acetylcholine receptors (nAChR) is an important nicotinic acetylcholine receptors subtype and closely associated with cognitive disorders, such as Alzheimer’s and schizophrenia disease. The mutant ArIB (V11L, V16A) of α-conotoxin ArIB with 17-amino acid residues specifically targets α7...
Autores principales: | Liu, Yanli, Yin, Yifeng, Song, Yunyang, Wang, Kang, Wu, Fanghui, Jiang, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460214/ https://www.ncbi.nlm.nih.gov/pubmed/32806654 http://dx.doi.org/10.3390/md18080422 |
Ejemplares similares
-
Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs
por: Ho, Thao N.T., et al.
Publicado: (2021) -
Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs
por: Lin, Bo, et al.
Publicado: (2016) -
The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site
por: Gulsevin, Alican, et al.
Publicado: (2021) -
AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity
por: Dutertre, Sébastien, et al.
Publicado: (2007) -
Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations
por: Yu, Rilei, et al.
Publicado: (2011)