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Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center

The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the...

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Autores principales: Nitzsche, Katharina, Fitze, Guido, Rüdiger, Mario, Birdir, Cahit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460378/
https://www.ncbi.nlm.nih.gov/pubmed/32751744
http://dx.doi.org/10.3390/diagnostics10080540
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author Nitzsche, Katharina
Fitze, Guido
Rüdiger, Mario
Birdir, Cahit
author_facet Nitzsche, Katharina
Fitze, Guido
Rüdiger, Mario
Birdir, Cahit
author_sort Nitzsche, Katharina
collection PubMed
description The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the timing of delivery and therapy. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 34 cases of gastroschisis between the years 2007 and 2017. A total of 34 fetuses with gastroschisis were examined and 33 outcomes registered: 22 cases of simple gastroschisis (66.7%) and 11 cases of complex gastroschisis (33.3%). A cut-off value of 18 mm for intraabdominal bowel dilatation (IABD) showed a positive predictive value (PPV) of 100% for predicting simple gastroschisis. IABD gives the best prediction for simple versus complex gastroschisis (cut-off of 18 mm). Extra-abdominal bowel dilatation (EABD) cut-off values of 10 mm and 18 mm showed low sensitivity and specificity to predict complex gastroschisis.
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spelling pubmed-74603782020-09-02 Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center Nitzsche, Katharina Fitze, Guido Rüdiger, Mario Birdir, Cahit Diagnostics (Basel) Article The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the timing of delivery and therapy. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 34 cases of gastroschisis between the years 2007 and 2017. A total of 34 fetuses with gastroschisis were examined and 33 outcomes registered: 22 cases of simple gastroschisis (66.7%) and 11 cases of complex gastroschisis (33.3%). A cut-off value of 18 mm for intraabdominal bowel dilatation (IABD) showed a positive predictive value (PPV) of 100% for predicting simple gastroschisis. IABD gives the best prediction for simple versus complex gastroschisis (cut-off of 18 mm). Extra-abdominal bowel dilatation (EABD) cut-off values of 10 mm and 18 mm showed low sensitivity and specificity to predict complex gastroschisis. MDPI 2020-07-30 /pmc/articles/PMC7460378/ /pubmed/32751744 http://dx.doi.org/10.3390/diagnostics10080540 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nitzsche, Katharina
Fitze, Guido
Rüdiger, Mario
Birdir, Cahit
Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title_full Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title_fullStr Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title_full_unstemmed Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title_short Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
title_sort prenatal prediction of outcome by fetal gastroschisis in a tertiary referral center
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460378/
https://www.ncbi.nlm.nih.gov/pubmed/32751744
http://dx.doi.org/10.3390/diagnostics10080540
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