Cargando…

Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020

The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention...

Descripción completa

Detalles Bibliográficos
Autores principales: Campisi, Giuseppina, Mauceri, Rodolfo, Bertoldo, Francesco, Bettini, Giordana, Biasotto, Matteo, Colella, Giuseppe, Consolo, Ugo, Di Fede, Olga, Favia, Gianfranco, Fusco, Vittorio, Gabriele, Mario, Lo Casto, Antonio, Lo Muzio, Lorenzo, Marcianò, Antonia, Mascitti, Marco, Meleti, Marco, Mignogna, Michele D., Oteri, Giacomo, Panzarella, Vera, Romeo, Umberto, Santarelli, Andrea, Vescovi, Paolo, Marchetti, Claudio, Bedogni, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460511/
https://www.ncbi.nlm.nih.gov/pubmed/32824826
http://dx.doi.org/10.3390/ijerph17165998
_version_ 1783576618653974528
author Campisi, Giuseppina
Mauceri, Rodolfo
Bertoldo, Francesco
Bettini, Giordana
Biasotto, Matteo
Colella, Giuseppe
Consolo, Ugo
Di Fede, Olga
Favia, Gianfranco
Fusco, Vittorio
Gabriele, Mario
Lo Casto, Antonio
Lo Muzio, Lorenzo
Marcianò, Antonia
Mascitti, Marco
Meleti, Marco
Mignogna, Michele D.
Oteri, Giacomo
Panzarella, Vera
Romeo, Umberto
Santarelli, Andrea
Vescovi, Paolo
Marchetti, Claudio
Bedogni, Alberto
author_facet Campisi, Giuseppina
Mauceri, Rodolfo
Bertoldo, Francesco
Bettini, Giordana
Biasotto, Matteo
Colella, Giuseppe
Consolo, Ugo
Di Fede, Olga
Favia, Gianfranco
Fusco, Vittorio
Gabriele, Mario
Lo Casto, Antonio
Lo Muzio, Lorenzo
Marcianò, Antonia
Mascitti, Marco
Meleti, Marco
Mignogna, Michele D.
Oteri, Giacomo
Panzarella, Vera
Romeo, Umberto
Santarelli, Andrea
Vescovi, Paolo
Marchetti, Claudio
Bedogni, Alberto
author_sort Campisi, Giuseppina
collection PubMed
description The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention (primary and secondary). The present paper reports the update of the conclusions from the Consensus Conference—held at the Symposium of the Italian Society of Oral Pathology and Medicine (SIPMO) (20 October 2018, Ancona, Italy)—after the newest recommendations (2020) on MRONJ were published by two scientific societies (Italian Societies of Maxillofacial Surgery and Oral Pathology and Medicine, SICMF and SIPMO), written on the inputs of the experts of the Italian Allied Committee on ONJ (IAC-ONJ). The conference focused on the topic of MRONJ, and in particular on the common practices at risk of inappropriateness in MRONJ diagnosis and therapy, as well as on MRONJ prevention and the dental management of patients at risk of MRONJ. It is a matter of cancer and osteometabolic patients that are at risk since being exposed to several drugs with antiresorptive (i.e., bisphosphonates and denosumab) or, more recently, antiangiogenic activities. At the same time, the Conference traced for dentists and oral surgeons some easy applicable indications and procedures to reduce MRONJ onset risk and to diagnose it early. Continuous updating on these issues, so important for the patient community, is recommended.
format Online
Article
Text
id pubmed-7460511
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-74605112020-09-03 Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020 Campisi, Giuseppina Mauceri, Rodolfo Bertoldo, Francesco Bettini, Giordana Biasotto, Matteo Colella, Giuseppe Consolo, Ugo Di Fede, Olga Favia, Gianfranco Fusco, Vittorio Gabriele, Mario Lo Casto, Antonio Lo Muzio, Lorenzo Marcianò, Antonia Mascitti, Marco Meleti, Marco Mignogna, Michele D. Oteri, Giacomo Panzarella, Vera Romeo, Umberto Santarelli, Andrea Vescovi, Paolo Marchetti, Claudio Bedogni, Alberto Int J Environ Res Public Health Conference Report The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists and oral surgeons involved in MRONJ prevention (primary and secondary). The present paper reports the update of the conclusions from the Consensus Conference—held at the Symposium of the Italian Society of Oral Pathology and Medicine (SIPMO) (20 October 2018, Ancona, Italy)—after the newest recommendations (2020) on MRONJ were published by two scientific societies (Italian Societies of Maxillofacial Surgery and Oral Pathology and Medicine, SICMF and SIPMO), written on the inputs of the experts of the Italian Allied Committee on ONJ (IAC-ONJ). The conference focused on the topic of MRONJ, and in particular on the common practices at risk of inappropriateness in MRONJ diagnosis and therapy, as well as on MRONJ prevention and the dental management of patients at risk of MRONJ. It is a matter of cancer and osteometabolic patients that are at risk since being exposed to several drugs with antiresorptive (i.e., bisphosphonates and denosumab) or, more recently, antiangiogenic activities. At the same time, the Conference traced for dentists and oral surgeons some easy applicable indications and procedures to reduce MRONJ onset risk and to diagnose it early. Continuous updating on these issues, so important for the patient community, is recommended. MDPI 2020-08-18 2020-08 /pmc/articles/PMC7460511/ /pubmed/32824826 http://dx.doi.org/10.3390/ijerph17165998 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Conference Report
Campisi, Giuseppina
Mauceri, Rodolfo
Bertoldo, Francesco
Bettini, Giordana
Biasotto, Matteo
Colella, Giuseppe
Consolo, Ugo
Di Fede, Olga
Favia, Gianfranco
Fusco, Vittorio
Gabriele, Mario
Lo Casto, Antonio
Lo Muzio, Lorenzo
Marcianò, Antonia
Mascitti, Marco
Meleti, Marco
Mignogna, Michele D.
Oteri, Giacomo
Panzarella, Vera
Romeo, Umberto
Santarelli, Andrea
Vescovi, Paolo
Marchetti, Claudio
Bedogni, Alberto
Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title_full Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title_fullStr Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title_full_unstemmed Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title_short Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020
title_sort medication-related osteonecrosis of jaws (mronj) prevention and diagnosis: italian consensus update 2020
topic Conference Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460511/
https://www.ncbi.nlm.nih.gov/pubmed/32824826
http://dx.doi.org/10.3390/ijerph17165998
work_keys_str_mv AT campisigiuseppina medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT maucerirodolfo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT bertoldofrancesco medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT bettinigiordana medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT biasottomatteo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT colellagiuseppe medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT consolougo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT difedeolga medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT faviagianfranco medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT fuscovittorio medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT gabrielemario medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT locastoantonio medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT lomuziolorenzo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT marcianoantonia medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT mascittimarco medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT meletimarco medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT mignognamicheled medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT oterigiacomo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT panzarellavera medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT romeoumberto medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT santarelliandrea medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT vescovipaolo medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT marchetticlaudio medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020
AT bedognialberto medicationrelatedosteonecrosisofjawsmronjpreventionanddiagnosisitalianconsensusupdate2020