Cargando…

Non-Small-Cell Lung Cancer-Sensitive Detection of the p.Thr790Met EGFR Alteration by Preamplification before PNA-Mediated PCR Clamping and Pyrosequencing

Targeted therapies and, more precisely, EGFR tyrosine kinase inhibitors (TKIs) have been a major improvement in the therapeutic management of EGFR-mutated non-small-cell lung cancers (NSCLCs). Earlier administration of these TKIs throughout tumor progression is imperative to improve patient outcomes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Billaud, Amandine, Verriele, Veronique, Dauvé, Jonathan, Chevalier, Louise-Marie, Morel, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460542/ https://www.ncbi.nlm.nih.gov/pubmed/32751202 http://dx.doi.org/10.3390/diagnostics10080527

Ejemplares similares

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation
por: Guha, Minakshi, et al.
Publicado: (2013)

Kir2.2 p.Thr140Met: a genetic susceptibility to sporadic periodic paralysis
por: FAN, CHUNXIANG, et al.
Publicado: (2018)

Myocardial Infarction and AGT p.Thr174Met Polymorphism: A Meta-Analysis of 7657 Subjects
por: Li, Yan-yan, et al.
Publicado: (2021)

Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping
por: Kim, Hye-Ryoun, et al.
Publicado: (2013)

CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report
por: Romozzi, Marina, et al.
Publicado: (2021)

Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples
por: Keppens, Cleo, et al.
Publicado: (2020)

Association between XRCC3 p.Thr241Met polymorphism and risk of glioma: A systematic review and meta-analysis
por: Tan, Shing Cheng, et al.
Publicado: (2022)

Preamplification Procedure for the Analysis of Ancient DNA Samples
por: Del Gaudio, Stefania, et al.
Publicado: (2013)

Magnetic resonance imaging with optical preamplification and detection
por: Simonsen, A., et al.
Publicado: (2019)

EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method
por: Watanabe, Kana, et al.
Publicado: (2016)

Comparison of Direct Sequencing, PNA Clamping-Real Time Polymerase Chain Reaction, and Pyrosequencing Methods for the Detection of EGFR Mutations in Non-small Cell Lung Carcinoma and the Correlation with Clinical Responses to EGFR Tyrosine Kinase Inhibitor Treatment
por: Lee, Hyun Ju, et al.
Publicado: (2013)

Variable phenotypic expression of nonsense mutation p.Thr5* in the APOE gene
por: Leren, Trond P., et al.
Publicado: (2016)

Properties of targeted preamplification in DNA and cDNA quantification
por: Andersson, Daniel, et al.
Publicado: (2015)

Global preamplification simplifies targeted mRNA quantification
por: Kroneis, Thomas, et al.
Publicado: (2017)

Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophrenia
por: Zhou, Zhifan, et al.
Publicado: (2016)

Familial Hemiplegic Migraine With Progressive Cerebellar Ataxia Caused by a p.Thr666Met CACNA1A Gene Mutation in a Chinese Family
por: Li, Mengmeng, et al.
Publicado: (2019)

Dual MET–EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer
por: Tang, Z, et al.
Publicado: (2008)

Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies
por: Noutsias, Michel, et al.
Publicado: (2008)

Preamplification with dUTP and Cod UNG Enables Elimination of Contaminating Amplicons
por: Andersson, Daniel, et al.
Publicado: (2018)

Technical Validation and Clinical Implications of Ultrasensitive PCR Approaches for EGFR-Thr790Met Mutation Detection in Pretreatment FFPE Samples and in Liquid Biopsies from Non-Small Cell Lung Cancer Patients
por: Simarro, Javier, et al.
Publicado: (2022)

Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation
por: Ruppert, Misty, et al.
Publicado: (2020)

EGFR Thr790Leu as a Potential Resistance Mechanism to First-Generation EGFR Tyrosine Kinase Inhibitor May Respond to Osimertinib in Patients With Lung Adenocarcinoma
por: Xiang, Chan, et al.
Publicado: (2021)

Early detection of circulating tumor DNA and successful treatment with osimertinib in thr790met-positive leptomeningeal metastatic lung cancer: A case report
por: Xu, Li-Qing, et al.
Publicado: (2022)

PSEN1 p.Thr116Ile Variant in Two Korean Families with Young Onset Alzheimer’s Disease
por: Bagyinszky, Eva, et al.
Publicado: (2018)

Silent variant in F8:c.222G>T (p.Thr74Thr) causes a partial exon skipping in a patient with mild hemophilia A
por: Letelier, Anna, et al.
Publicado: (2021)

Rapid detection by hydrops panel of Noonan syndrome with PTPN11 mutation (p.Thr73Ile) and persistent thrombocytopenia
por: Schönfeld, Mascha, et al.
Publicado: (2020)

Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma
por: Alhelf, Maha, et al.
Publicado: (2023)

CHCHD2 p.Thr61Ile knock‐in mice exhibit motor defects and neuropathological features of Parkinson's disease
por: Fan, Liyuan, et al.
Publicado: (2022)

PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer
por: Fouz, Munira F., et al.
Publicado: (2020)

Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling
por: Zeke, András, et al.
Publicado: (2022)

PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer
por: Han, Ji-Youn, et al.
Publicado: (2016)

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis
por: Kim, Chang Gon, et al.
Publicado: (2017)

Type 2 deiodinase p.Thr92Ala polymorphism does not affect the severity of obesity and weight loss after bariatric surgery
por: Benenati, Nicoletta, et al.
Publicado: (2022)

Jumping the green wall: The use of PNA‐DNA clamps to enhance microbiome sampling depth in wildlife microbiome research
por: Víquez‐R, Luis, et al.
Publicado: (2020)

Erratum to: PNA clamping-assisted fluorescence melting curve analysis for detecting EGFR and KRAS mutations in the circulating tumor DNA of patients with advanced non-small cell lung cancer
por: Han, Ji-Youn, et al.
Publicado: (2016)

Multiplex preamplification of specific cDNA targets prior to gene expression analysis by TaqMan Arrays
por: Mengual, Lourdes, et al.
Publicado: (2008)

EGFR T790M: revealing the secrets of a gatekeeper
por: Ko, Brian, et al.
Publicado: (2017)

The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer
por: Gou, Lan-Ying, et al.
Publicado: (2016)

Association between the p.Thr1406Asn polymorphism of the carbamoyl-phosphate synthetase 1 gene and necrotizing enterocolitis: A prospective multicenter study
por: Moonen, Rob M., et al.
Publicado: (2016)

The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant
por: Corvillo, Fernando, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m7sqhp5lr7m3loca6vgolr967g