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Osteoclasts’ Ability to Generate Trenches Rather Than Pits Depends on High Levels of Active Cathepsin K and Efficient Clearance of Resorption Products

Until recently, it was well-accepted that osteoclasts resorb bone according to the resorption cycle model. This model is based on the assumption that osteoclasts are immobile during bone erosion, allowing the actin ring to be firmly attached and thereby provide an effective seal encircling the resor...

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Detalles Bibliográficos
Autores principales: Borggaard, Xenia G., Pirapaharan, Dinisha C., Delaissé, Jean-Marie, Søe, Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460581/
https://www.ncbi.nlm.nih.gov/pubmed/32824687
http://dx.doi.org/10.3390/ijms21165924