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Osteoclasts’ Ability to Generate Trenches Rather Than Pits Depends on High Levels of Active Cathepsin K and Efficient Clearance of Resorption Products
Until recently, it was well-accepted that osteoclasts resorb bone according to the resorption cycle model. This model is based on the assumption that osteoclasts are immobile during bone erosion, allowing the actin ring to be firmly attached and thereby provide an effective seal encircling the resor...
Autores principales: | Borggaard, Xenia G., Pirapaharan, Dinisha C., Delaissé, Jean-Marie, Søe, Kent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460581/ https://www.ncbi.nlm.nih.gov/pubmed/32824687 http://dx.doi.org/10.3390/ijms21165924 |
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