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Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation

HIV transactivator protein (Tat) plays a pivotal role in viral replication through modulation of cellular transcription factors and transactivation of viral genomic transcription. The effect of HIV-1 Tat on reverse transcription has long been described in the literature, however, that of HIV-2 is un...

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Detalles Bibliográficos
Autores principales:	Szojka, Zsófia, Mótyán, János András, Miczi, Márió, Mahdi, Mohamed, Tőzsér, József
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460587/ https://www.ncbi.nlm.nih.gov/pubmed/32824587 http://dx.doi.org/10.3390/ijms21165907

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