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Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network

The Rho guanine nucleotide exchange factor (RGNEF) protein encoded by the ARHGEF28 gene has been implicated in the neurodegenerative disease amyotrophic lateral sclerosis (ALS). Biochemical and pathological studies have shown that RGNEF is a component of the hallmark neuronal cytoplasmic inclusions...

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Detalles Bibliográficos
Autores principales:	Di Gregorio, Sonja E., Volkening, Kathryn, Strong, Michael J., Duennwald, Martin L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460592/ https://www.ncbi.nlm.nih.gov/pubmed/32764283 http://dx.doi.org/10.3390/ijms21165597

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