Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE

The increasing number of Alzheimer’s disease (AD) cases requires the development of new improved drug candidates, possessing the ability of more efficient treatment as well as less unwanted side effects. Cholinesterase enzymes are highly associated with the development of AD and thus represent impor...

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Detalles Bibliográficos
Autores principales: Kladnik, Jerneja, Ristovski, Samuel, Kljun, Jakob, Defant, Andrea, Mancini, Ines, Sepčić, Kristina, Turel, Iztok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460603/
https://www.ncbi.nlm.nih.gov/pubmed/32781544
http://dx.doi.org/10.3390/ijms21165628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460603/
https://www.ncbi.nlm.nih.gov/pubmed/32781544
http://dx.doi.org/10.3390/ijms21165628

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