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IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle
Mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDH2) catalyzes the oxidative decarboxylation of isocitrate into α-ketoglutarate with concurrent reduction of NADP(+) to NADPH. However, it is not fully understood how IDH2 is intertwined with muscle development and fatty acid metabolism. Her...
Autores principales: | Pan, Jeong Hoon, Tang, Jingsi, Kim, Young Jun, Lee, Jin Hyup, Shin, Eui-Cheol, Zhao, Jiangchao, Kim, Kee-Hong, Hwang, Kyung A., Huang, Yan, Kim, Jae Kyeom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460611/ https://www.ncbi.nlm.nih.gov/pubmed/32764267 http://dx.doi.org/10.3390/ijms21165596 |
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