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Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer

Genome instability is an essential hallmark in tumor development, including colorectal cancer. We have recently identified the oxysterol binding protein-related protein 3 (ORP3), also known as oxysterol binding protein-like 3 (OSBPL3), as a novel ploidy-control gene, whose knock-out leads to aneuplo...

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Detalles Bibliográficos
Autores principales: Xu, Pengfei, Richter, Julia, Blatz, Annette, Gärtner, Fabian, Alberts, Roland, Azoitei, Anca, Makori, Wycliffe Arika, Meessen, Sabine, Knippschild, Uwe, Günes, Cagatay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460621/
https://www.ncbi.nlm.nih.gov/pubmed/32824360
http://dx.doi.org/10.3390/ijms21165894