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Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway
BACKGROUND: Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. Additional compounds with promising anticancer effects such as AKBA (Acetyl...
Autores principales: | Al-Bahlani, Shadia, Burney, Ikram A., Al-Dhahli, Buthaina, Al-Kharusi, Safiya, Al-Kharousi, Fakhra, Al-Kalbani, Amani, Ahmed, Ikhlas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460741/ https://www.ncbi.nlm.nih.gov/pubmed/32867831 http://dx.doi.org/10.1186/s40360-020-00442-1 |
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