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The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts

The Cpi-17 (ppp1r14) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1) inhibitors. When phosphorylated, Cpi-17 is a potent inhibitor of myosin phosphatase (MP), a holoenzyme complex of the regulatory subunit Mypt1 and the catalytic subunit PP1. Myos...

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Detalles Bibliográficos
Autores principales: Lang, Irene, Virk, Guneet, Zheng, Dale C., Young, Jason, Nguyen, Michael J., Amiri, Rojin, Fong, Michelle, Arata, Alisa, Chadaideh, Katia S., Walsh, Susan, Weiser, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460850/
https://www.ncbi.nlm.nih.gov/pubmed/32784920
http://dx.doi.org/10.3390/ijms21165709