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Indomethacin Increases Quercetin Affinity for Human Serum Albumin: A Combined Experimental and Computational Study and Its Broader Implications

Human serum albumin (HSA) is the most abundant carrier protein in the human body. Competition for the same binding site between different ligands can lead to an increased active concentration or a faster elimination of one or both ligands. Indomethacin and quercetin both bind to the binding site loc...

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Detalles Bibliográficos
Autores principales: Rimac, Hrvoje, Tandarić, Tana, Vianello, Robert, Bojić, Mirza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460863/
https://www.ncbi.nlm.nih.gov/pubmed/32785199
http://dx.doi.org/10.3390/ijms21165740