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Indomethacin Increases Quercetin Affinity for Human Serum Albumin: A Combined Experimental and Computational Study and Its Broader Implications
Human serum albumin (HSA) is the most abundant carrier protein in the human body. Competition for the same binding site between different ligands can lead to an increased active concentration or a faster elimination of one or both ligands. Indomethacin and quercetin both bind to the binding site loc...
Autores principales: | Rimac, Hrvoje, Tandarić, Tana, Vianello, Robert, Bojić, Mirza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460863/ https://www.ncbi.nlm.nih.gov/pubmed/32785199 http://dx.doi.org/10.3390/ijms21165740 |
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