COVID‐19 during pregnancy: non‐reassuring fetal heart rate, placental pathology and coagulopathy

We report a case of a pregnant woman with COVID‐19 who developed coagulopathy in the absence of severe clinical symptoms. A polymerase chain reaction test of a vaginal swab was positive for SARS‐CoV‐2 RNA, suggesting a possibility of perinatal transmission. Cesarean delivery was performed because of...

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Detalles Bibliográficos
Autores principales: Mongula, J. E., Frenken, M. W. E., van Lijnschoten, G., Arents, N. L. A., de Wit‐Zuurendonk, L. D., Schimmel‐de Kok, A. P. A., van Runnard Heimel, P. J., Porath, M. M., Goossens, S. M. T. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461013/
https://www.ncbi.nlm.nih.gov/pubmed/32853442
http://dx.doi.org/10.1002/uog.22189
Descripción
Sumario:We report a case of a pregnant woman with COVID‐19 who developed coagulopathy in the absence of severe clinical symptoms. A polymerase chain reaction test of a vaginal swab was positive for SARS‐CoV‐2 RNA, suggesting a possibility of perinatal transmission. Cesarean delivery was performed because of a non‐reassuring fetal heart rate; the placenta showed increased perivillous fibrin deposition and intervillositis. Moreover, placental infection with SARS‐CoV‐2 was demonstrated by placental immunostaining. The findings suggest a possible relationship between placental fibrin deposition and chronic and acute intervillositis, non‐reassuring fetal heart rate and coagulopathy in pregnant women with COVID‐19. © 2020 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

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