Cargando…
Correct Identification of Cell of Origin May Explain Many Aspects of Cancer: The Role of Neuroendocrine Cells as Exemplified from the Stomach
Cancers are believed to originate from stem cells. Previously, the hypothesis was that tumors developed due to dedifferentiation of mature cells. We studied the regulation of gastric acid secretion and showed that gastrin through the gastrin receptor stimulates enterochromaffin-like (ECL) cell hista...
Autores principales: | Waldum, Helge, Mjønes, Patricia G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461029/ https://www.ncbi.nlm.nih.gov/pubmed/32796591 http://dx.doi.org/10.3390/ijms21165751 |
Ejemplares similares
-
Time to Classify Tumours of the Stomach and the Kidneys According to Cell of Origin
por: Waldum, Helge, et al.
Publicado: (2021) -
Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift
por: Waldum, Helge L., et al.
Publicado: (2018) -
Towards Understanding of Gastric Cancer Based upon Physiological Role of Gastrin and ECL Cells
por: Waldum, Helge, et al.
Publicado: (2020) -
The central role of gastrin in gastric cancer
por: Waldum, Helge, et al.
Publicado: (2023) -
The Enterochromaffin-like [ECL] Cell—Central in Gastric Physiology and Pathology
por: Waldum, Helge L., et al.
Publicado: (2019)