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Regen med therapeutic opportunities for fighting COVID‐19

This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID‐19. This article addresses why SARS‐CoV‐2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeu...

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Autores principales: Atala, Anthony, Henn, Alicia, Lundberg, Martha, Ahsan, Taby, Greenberg, Jordan, Krukin, Jeff, Lynum, Steven, Lutz, Cat, Cetrulo, Kyle, Albanna, Mohammad, Pereira, Taciana, Eaker, Shannon, Hunsberger, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461298/
https://www.ncbi.nlm.nih.gov/pubmed/32856432
http://dx.doi.org/10.1002/sctm.20-0245
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author Atala, Anthony
Henn, Alicia
Lundberg, Martha
Ahsan, Taby
Greenberg, Jordan
Krukin, Jeff
Lynum, Steven
Lutz, Cat
Cetrulo, Kyle
Albanna, Mohammad
Pereira, Taciana
Eaker, Shannon
Hunsberger, Joshua
author_facet Atala, Anthony
Henn, Alicia
Lundberg, Martha
Ahsan, Taby
Greenberg, Jordan
Krukin, Jeff
Lynum, Steven
Lutz, Cat
Cetrulo, Kyle
Albanna, Mohammad
Pereira, Taciana
Eaker, Shannon
Hunsberger, Joshua
author_sort Atala, Anthony
collection PubMed
description This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID‐19. This article addresses why SARS‐CoV‐2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeutic opportunities to battle COVID‐19. We describe animal models that depict the mechanism of action for COVID‐19 and that may help identify new treatments. Additionally, organoid platforms that can recapitulate some of the physiological properties of human organ systems, such as the lungs and the heart, are discussed as potential platforms that may prove useful in rapidly screening new drugs and identifying at‐risk patients. This article critically evaluates some of the promising regenerative medicine‐based therapies for treating COVID‐19 and presents some of the collective technologies and resources that the scientific community currently has available to confront this pandemic.
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spelling pubmed-74612982020-09-02 Regen med therapeutic opportunities for fighting COVID‐19 Atala, Anthony Henn, Alicia Lundberg, Martha Ahsan, Taby Greenberg, Jordan Krukin, Jeff Lynum, Steven Lutz, Cat Cetrulo, Kyle Albanna, Mohammad Pereira, Taciana Eaker, Shannon Hunsberger, Joshua Stem Cells Transl Med Perspectives This perspective from a Regenerative Medicine Manufacturing Society working group highlights regenerative medicine therapeutic opportunities for fighting COVID‐19. This article addresses why SARS‐CoV‐2 is so different from other viruses and how regenerative medicine is poised to deliver new therapeutic opportunities to battle COVID‐19. We describe animal models that depict the mechanism of action for COVID‐19 and that may help identify new treatments. Additionally, organoid platforms that can recapitulate some of the physiological properties of human organ systems, such as the lungs and the heart, are discussed as potential platforms that may prove useful in rapidly screening new drugs and identifying at‐risk patients. This article critically evaluates some of the promising regenerative medicine‐based therapies for treating COVID‐19 and presents some of the collective technologies and resources that the scientific community currently has available to confront this pandemic. John Wiley & Sons, Inc. 2020-08-27 /pmc/articles/PMC7461298/ /pubmed/32856432 http://dx.doi.org/10.1002/sctm.20-0245 Text en © 2020 The Authors. stem cells translational medicine published by Wiley Periodicals LLC on behalf of AlphaMed Press. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspectives
Atala, Anthony
Henn, Alicia
Lundberg, Martha
Ahsan, Taby
Greenberg, Jordan
Krukin, Jeff
Lynum, Steven
Lutz, Cat
Cetrulo, Kyle
Albanna, Mohammad
Pereira, Taciana
Eaker, Shannon
Hunsberger, Joshua
Regen med therapeutic opportunities for fighting COVID‐19
title Regen med therapeutic opportunities for fighting COVID‐19
title_full Regen med therapeutic opportunities for fighting COVID‐19
title_fullStr Regen med therapeutic opportunities for fighting COVID‐19
title_full_unstemmed Regen med therapeutic opportunities for fighting COVID‐19
title_short Regen med therapeutic opportunities for fighting COVID‐19
title_sort regen med therapeutic opportunities for fighting covid‐19
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461298/
https://www.ncbi.nlm.nih.gov/pubmed/32856432
http://dx.doi.org/10.1002/sctm.20-0245
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