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Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice
BACKGROUND: Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer’s disease (AD)-like pathological changes. However, it is largely unknown whether BaP exposure participates in the disease progression of AD. OBJECTIVES: To investigate the effect of BaP exposure...
Autores principales: | Liu, Dan, Zhao, Yujia, Qi, Yuze, Gao, Yun, Tu, Dezhen, Wang, Yinxi, Gao, Hui-Ming, Zhou, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461337/ https://www.ncbi.nlm.nih.gov/pubmed/32867800 http://dx.doi.org/10.1186/s12974-020-01925-y |
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