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Suppression of SHROOM1 Improves In Vitro and In Vivo Gene Integration by Promoting Homology-Directed Repair

Homologous recombination (HR) is often used to achieve targeted gene integration because of its higher precision and operability compared with microhomology-mediated end-joining (MMEJ) or non-homologous end-joining (NHEJ). It appears to be inefficient for gene integration in animal cells and embryos...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhihua, Zhang, Hanshuo, Xiong, Tuanlin, Wang, Junyi, Yang, Di, Zhu, Dan, Li, Juan, Yang, Ye, Sun, Changhong, Zhao, Yuting, Xi, Jianzhong Jeff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461567/ https://www.ncbi.nlm.nih.gov/pubmed/32823670 http://dx.doi.org/10.3390/ijms21165821

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