Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder related to age, characterized by the cerebral deposition of fibrils, which are made from the amyloid-β (Aβ), a peptide of 40–42 amino acids. The conversion of Aβ into neurotoxic oligomeric, fibrillar, and protofibrillar assemb...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Sahab, Kabir, Md. Tanvir, Rahman, Md. Sohanur, Behl, Tapan, Jeandet, Philippe, Ashraf, Ghulam Md, Najda, Agnieszka, Bin-Jumah, May N., El-Seedi, Hesham R., Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461598/
https://www.ncbi.nlm.nih.gov/pubmed/32824102
http://dx.doi.org/10.3390/ijms21165858

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